Across TCGA pan-cancer cohorts, MIR513C RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR513C’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR513C RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR513C is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.
KIRC, KIRP, and COAD are the cancer types where MIR513C tumor–normal differential expression is most reproducible.