MIR512-2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR512-2 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated MIR512-2 data layer compared with 1 for mutation status.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher MIR512-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR512-2 expression acts as an unfavorable survival marker.

TGCT, ESCA, and PAAD are the cancer types where MIR512-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
TGCTOSTertileIII,IV0.0031.000<.00190view →
ESCAOSTertileAll0.2200.707<.00181view →
PAADOSTertileAll0.1070.640<.00172view →
UCECOSTertileAll0.1480.682<.00148view →
CESCDFSTertileAll0.1380.740<.00118view →
STADOSTertileII,III,IV0.0610.711<.00118view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration