Across TCGA patient cohorts, MIR509-2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MIR509-2-associated genes across cancer lineages are MIR1179, CENPVL1, and RNU6-473P. Each is linked with MIR509-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR509-2-to-partner and partner-to-MIR509-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR509-2→partner) and Y-score (partner→MIR509-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR1179 →	+0.253	+7.954	<.001	.008	3	1
HNSC	CENPVL1 →	+0.024	+7.954	<.001	.008	3	1
HNSC	RNU6-473P →	+0.263	+7.954	<.001	.008	3	1
HNSC	MIR3683 →	+0.398	+7.954	<.001	.008	3	1
UCEC	RN7SKP135 →	+0.173	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

MIR509-2 survival (RNA) · tumor vs normal (RNA) · all MIR509-2 data types