MIR5089

Across TCGA pan-cancer cohorts, MIR5089 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR5089’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR5089 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR5089 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

KIRC, BLCA, and THCA are the cancer types where MIR5089 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR5089 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.138	<.001	8	view →
BLCA	All	All	+0.297	.023	4	view →
THCA	All	All	−0.082	.022	3	view →
LUAD	Male	All	−0.271	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR5089–KIRC

Open the KIRC breakdown →