MIR5088

Across TCGA patient cohorts, MIR5088 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,373 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MIR5088-associated GO terms across cancer lineages are Positive regulation of canonical NF-kappaB signal transduction, Canonical NF-kappaB signal transduction, and Regulation of actin filament organization. Each is linked with MIR5088 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIR5088-to-partner and partner-to-MIR5088 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of canonical NF-kappaB signal transduction grouped by MIR5088-low versus MIR5088-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR5088→partner) and Y-score (partner→MIR5088) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Positive regulation of canonical NF-kappaB signal transduction →	+0.058	+0.078	<.001	<.001	3	4
HNSC	Canonical NF-kappaB signal transduction →	+0.052	+0.074	<.001	<.001	3	4
HNSC	Regulation of actin filament organization →	+0.047	+0.042	<.001	<.001	3	4
HNSC	Cellular response to radiation →	+0.060	+0.059	<.001	<.001	3	4
HNSC	Organelle disassembly →	+0.056	+0.066	<.001	<.001	3	4
HNSC	Negative regulation of mRNA metabolic process →	+0.058	+0.076	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,373 associations by consensus.

Positive regulation of canonical NF-kappaB signal transduction by MIR5088 expression — HNSC

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