Across TCGA patient cohorts, MIR506 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR506-associated genes across cancer lineages are RNU6-1205P, RNA5SP205, and RNA5SP436. Each is linked with MIR506 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR506-to-partner and partner-to-MIR506 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR506→partner) and Y-score (partner→MIR506) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1205P →	+0.806	+4.690	<.001	.003	3	1
UCEC	RNA5SP205 →	+0.797	+4.852	<.001	.006	3	1
UCEC	RNA5SP436 →	+0.587	+4.937	<.001	.005	3	1
UCEC	LINC02307 →	+0.442	+5.386	<.001	.001	3	1
UCEC	MIR3180-4 →	+0.432	+5.226	<.001	.003	3	1
UCEC	MIR4445 →	+0.813	+7.478	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

MIR506 survival (RNA) · tumor vs normal (RNA) · all MIR506 data types