Across TCGA pan-cancer cohorts, MIR503HG RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated MIR503HG data layer compared with 1 for mutation status.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MIR503HG RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR503HG expression acts as an unfavorable survival marker, although some lineages such as THCA and UCS show a favorable association.
ACC, UVM, and MESO are the cancer types where MIR503HG RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.