Across TCGA pan-cancer cohorts, MIR5009 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR5009’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR5009 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR5009 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
LUSC and KICH are the cancer types where MIR5009 tumor–normal differential expression is most reproducible.