Across TCGA patient cohorts, MIR496 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR496-associated genes across cancer lineages are RPL7AP23, ANK2-AS1, and NREP-AS1. Each is linked with MIR496 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR496-to-partner and partner-to-MIR496 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR496→partner) and Y-score (partner→MIR496) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL7AP23 →	+0.064	+3.408	<.001	.009	3	1
SKCM	ANK2-AS1 →	+0.044	+3.501	.005	.005	3	1
SKCM	NREP-AS1 →	+0.039	+4.594	<.001	<.001	3	1
UCEC	MIR4476 →	+0.736	+8.066	<.001	.007	3	1
LUSC	FAM74A1 →	+0.169	+7.924	<.001	.008	3	1
LUSC	RNU6-1213P →	+0.343	+7.924	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

MIR496 survival (RNA) · tumor vs normal (RNA) · all MIR496 data types