Across TCGA patient cohorts, MIR491 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,187 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MIR491-associated proteins across cancer lineages are SYNE1, SNTB1, and IRF2BP2_S318. Each is linked with MIR491 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIR491-to-partner and partner-to-MIR491 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR491→partner) and Y-score (partner→MIR491) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SYNE1 →	+0.283	+0.722	.007	.001	3	4
HNSC	SNTB1 →	+0.486	+1.216	<.001	<.001	3	3
OV	IRF2BP2_S318 →	+0.997	+1.209	<.001	.007	3	3
UCEC	RCOR1_S460 →	-0.366	-0.850	.004	.009	3	3
BRCA	SMCHD1 →	-0.249	-0.731	.003	.002	3	3
OV	EIF5B_S1168 →	-0.594	-0.696	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,187 associations by consensus.

Exploration

MIR491 survival (RNA) · tumor vs normal (RNA) · all MIR491 data types