Across TCGA patient cohorts, MIR489 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,001 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR489-associated GO terms across cancer lineages are Embryonic organ morphogenesis, Negative regulation of canonical Wnt signaling pathway, and Establishment of protein localization to membrane. Each is linked with MIR489 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIR489-to-partner and partner-to-MIR489 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR489→partner) and Y-score (partner→MIR489) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Embryonic organ morphogenesis →	+0.113	+0.239	<.001	.002	3	4
ESCA	Negative regulation of canonical Wnt signaling pathway →	+0.138	+0.110	<.001	.007	2	4
ESCA	Establishment of protein localization to membrane →	+0.166	+0.190	<.001	.007	3	3
ESCA	Programmed cell death in response to reactive oxygen species →	+0.138	+0.232	<.001	.003	3	3
STAD	tRNA 5'-end processing →	+0.143	+0.121	<.001	<.001	3	3
ESCA	Negative regulation of cell development →	+0.124	+0.230	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,001 associations by consensus.

Exploration

MIR489 survival (RNA) · tumor vs normal (RNA) · all MIR489 data types