Across TCGA patient cohorts, MIR485 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR485-associated genes across cancer lineages are PDCD4, PKC-b-II_pS660, and Rb_pS807_S811. Each is linked with MIR485 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR485-to-partner and partner-to-MIR485 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR485→partner) and Y-score (partner→MIR485) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.627	-3.000	.021	.037	3	1
UCEC	PKC-b-II_pS660 →	-0.326	-3.000	.041	.037	3	1
UCEC	Rb_pS807_S811 →	-0.541	-3.000	.020	.037	3	1
UCEC	MEK1 →	+0.415	+3.000	.049	.037	2	1
UCEC	N-Ras →	+0.172	+3.013	.012	.019	2	1
UCEC	FASN →	+0.451	+3.000	.047	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

MIR485 survival (RNA) · tumor vs normal (RNA) · all MIR485 data types