Across TCGA pan-cancer cohorts, MIR4778 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MIR4778’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR4778 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4778 is over-expressed in tumor.
LUSC are the cancer types where MIR4778 tumor–normal differential expression is most reproducible.