MIR4776-1

Across TCGA pan-cancer cohorts, MIR4776-1 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated MIR4776-1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MIR4776-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4776-1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

UCEC, KIRC, and HNSC are the cancer types where MIR4776-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.230	0.840	<.001	72	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	42	view →
HNSC	DFS	Tertile	IV	0.648	0.308	.018	42	view →
LGG	DFS	Tertile	All	0.429	0.748	<.001	36	view →
SKCM	DFS	Tertile	All	0.211	0.728	.023	18	view →
STAD	DFS	Tertile	All	0.384	0.638	.017	18	view →
TGCT	DFS	Tertile	All	0.421	0.841	.023	18	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MIR4776-1–UCEC (DFS)

Open the UCEC breakdown →