MIR4759

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR4759 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,499 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4759-associated GO terms across cancer lineages are RNA polymerase II preinitiation complex assembly, Regulation of mRNA catabolic process, and Histone mRNA metabolic process. Each is linked with MIR4759 in more than 8 cancer types. Because this analysis shows association rather than direction, both MIR4759-to-partner and partner-to-MIR4759 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA polymerase II preinitiation complex assembly grouped by MIR4759-low versus MIR4759-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4759→partner) and Y-score (partner→MIR4759) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRNA polymerase II preinitiation complex assembly →+0.072+0.192<.001<.00139
ESCARegulation of mRNA catabolic process →+0.070+0.266<.001.00139
ESCAHistone mRNA metabolic process →+0.081+0.170<.001.00139
STADGlycerophospholipid metabolic process →+0.064+0.151<.001<.00139
ESCAProtein desumoylation →+0.078+0.167<.001.00239
ESCAModulation by host of viral genome replication →+0.070+0.229<.001.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,499 associations by consensus.

RNA polymerase II preinitiation complex assembly by MIR4759 expression — STAD

Box plot of RNA polymerase II preinitiation complex assembly in MIR4759-low vs MIR4759-high samples in STAD.

Explore this box plot interactively →

Exploration