MIR4757

Across TCGA pan-cancer cohorts, MIR4757 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR4757’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR4757 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR4757 is over-expressed in tumor, although a few such as BRCA and HNSC show the opposite, repressed pattern.

BRCA, HNSC, and THCA are the cancer types where MIR4757 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4757 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	−0.305	<.001	6	view →
HNSC	All	II,III,IV	−0.135	.004	6	view →
THCA	All	All	−0.207	.001	4	view →
LUAD	Male	All	−0.179	.039	1	view →
LUSC	All	All	−0.172	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MIR4757–BRCA

Open the BRCA breakdown →