MIR4756

Across TCGA pan-cancer cohorts, MIR4756 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR4756’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR4756 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4756 is over-expressed in tumor, although a few such as COAD and KIRP show the opposite, repressed pattern.

BRCA, COAD, and KIRP are the cancer types where MIR4756 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4756 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	+0.231	<.001	6	view →
COAD	Female	All	−0.264	.019	2	view →
KIRP	All	All	−0.080	.040	1	view →
KIRC	All	All	−0.037	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR4756–BRCA

Open the BRCA breakdown →