MIR4753

Across TCGA pan-cancer cohorts, MIR4753 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MIR4753 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MIR4753 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4753 expression acts as an unfavorable survival marker.

THCA, KIRP, and CHOL are the cancer types where MIR4753 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	II,III,IV	0.633	0.936	<.001	66	view →
KIRP	OS	Tertile	II,III,IV	0.111	0.769	<.001	42	view →
CHOL	OS	Tertile	IV	0.024	0.732	.014	36	view →
ESCA	OS	Median	All	0.449	1.000	.011	18	view →
TGCT	DFS	Tertile	All	0.600	0.817	.022	12	view →
STAD	DFS	Median	III,IV	0.462	0.671	.003	11	view →
MESO	DFS	Tertile	III,IV	0.195	0.428	.034	9	view →
GBM	OS	Tertile	All	0.089	0.415	.021	9	view →
KIRC	DFS	Tertile	All	0.453	0.663	.042	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MIR4753–THCA (OS)

Open the THCA breakdown →