Across TCGA pan-cancer cohorts, MIR4711 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR4711’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR4711 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4711 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
KIRC, KICH, and LIHC are the cancer types where MIR4711 tumor–normal differential expression is most reproducible.