MIR4681

Across TCGA pan-cancer cohorts, MIR4681 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR4681’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR4681 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4681 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

BRCA, ESCA, and STAD are the cancer types where MIR4681 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4681 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.148	.019	4	view →
ESCA	Male	All	−0.633	.039	1	view →
STAD	All	II,III,IV	+0.301	.018	1	view →
KIRC	All	All	+0.042	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR4681–BRCA

Open the BRCA breakdown →