MIR4676

Across TCGA patient cohorts, MIR4676 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,103 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4676-associated GO terms across cancer lineages are Positive regulation of peptidase activity, Muscle adaptation, and Glycerophospholipid metabolic process. Each is linked with MIR4676 in more than 8 cancer types. Because this analysis shows association rather than direction, both MIR4676-to-partner and partner-to-MIR4676 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of peptidase activity grouped by MIR4676-low versus MIR4676-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4676→partner) and Y-score (partner→MIR4676) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of peptidase activity →	+0.039	+0.503	<.001	.001	3	9
ESCA	Muscle adaptation →	+0.052	+1.013	<.001	<.001	3	9
STAD	Glycerophospholipid metabolic process →	+0.038	+0.704	<.001	<.001	3	8
ESCA	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress →	+0.060	+0.832	<.001	<.001	3	8
COAD	Regulation of epidermal growth factor-activated receptor activity →	+0.057	+0.250	<.001	.004	3	8
COAD	Positive regulation of intracellular protein transport →	+0.044	+0.154	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,103 associations by consensus.

Positive regulation of peptidase activity by MIR4676 expression — ESCA

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