MIR4665

Across TCGA pan-cancer cohorts, MIR4665 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MIR4665 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher MIR4665 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR4665 expression acts as an unfavorable survival marker, although some lineages such as ESCA and GBM show a favorable association.

ESCA, ACC, and GBM are the cancer types where MIR4665 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Quartile	All	0.637	0.375	.002	67	view →
ACC	DFS	Tertile	All	0.114	0.772	<.001	45	view →
GBM	OS	Tertile	All	0.366	0.229	.010	36	view →
LIHC	DFS	Tertile	III,IV	0.145	0.378	.002	27	view →
STAD	OS	Tertile	III,IV	0.692	0.259	.005	23	view →
KICH	OS	Quartile	II,III,IV	0.760	0.911	.034	19	view →
LUSC	DFS	Tertile	II,III,IV	0.435	0.626	.017	18	view →
LUAD	OS	Tertile	IV	0.114	0.560	.038	18	view →
SKCM	DFS	Tertile	All	0.360	0.184	.017	12	view →
BRCA	OS	Tertile	All	0.968	0.916	.017	12	view →
OV	DFS	Quartile	III,IV	0.565	0.481	.027	12	view →
LGG	DFS	Quartile	All	0.273	0.446	.007	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MIR4665–ESCA (DFS)

Open the ESCA breakdown →