MIR4661

Across TCGA pan-cancer cohorts, MIR4661 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR4661 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR4661 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4661 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

KIRC, SKCM, and UCEC are the cancer types where MIR4661 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.100	0.806	<.001	108	view →
SKCM	DFS	Tertile	All	0.270	0.740	<.001	90	view →
UCEC	DFS	Tertile	All	0.087	0.649	<.001	72	view →
KICH	DFS	Tertile	II,III,IV	0.353	0.889	.001	39	view →
LGG	OS	Tertile	All	0.191	0.810	<.001	36	view →
THCA	DFS	Tertile	IV	0.027	0.937	<.001	36	view →
CESC	DFS	Tertile	II,III,IV	0.173	0.705	.028	18	view →
PRAD	OS	Tertile	All	0.607	0.913	<.001	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
OV	DFS	Tertile	All	0.717	0.375	.039	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR4661–KIRC (OS)

Open the KIRC breakdown →