MIR4659A

Across TCGA patient cohorts, MIR4659A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,534 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MIR4659A-associated GO terms across cancer lineages are Regulation of telomere maintenance via telomere lengthening, Nucleotide-excision repair, and Telomere maintenance via telomere lengthening. Each is linked with MIR4659A in more than 24 cancer types. Because this analysis shows association rather than direction, both MIR4659A-to-partner and partner-to-MIR4659A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance via telomere lengthening grouped by MIR4659A-low versus MIR4659A-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4659A→partner) and Y-score (partner→MIR4659A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Regulation of telomere maintenance via telomere lengthening →	+0.043	+1.179	<.001	<.001	3	25
UVM	Nucleotide-excision repair →	+0.038	+0.219	<.001	<.001	3	25
STAD	Telomere maintenance via telomere lengthening →	+0.042	+0.572	<.001	<.001	3	25
DLBC	Glycerolipid biosynthetic process →	+0.066	+0.485	<.001	.002	3	24
UVM	Glycerophospholipid biosynthetic process →	+0.047	+0.175	<.001	.001	3	24
ESCA	Rhythmic process →	+0.031	+0.427	.002	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,534 associations by consensus.

Regulation of telomere maintenance via telomere lengthening by MIR4659A expression — LAML

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