MIR4650-2

Across TCGA pan-cancer cohorts, MIR4650-2 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated MIR4650-2 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher MIR4650-2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4650-2 expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

KICH, KIRC, and GBM are the cancer types where MIR4650-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.237	0.860	<.001	72	view →
KIRC	DFS	Tertile	All	0.348	0.658	.001	69	view →
GBM	OS	Tertile	All	0.054	0.420	<.001	36	view →
STAD	DFS	Tertile	All	0.272	0.548	.029	18	view →
PRAD	OS	Tertile	All	0.960	0.995	.002	18	view →
OV	OS	Tertile	All	0.795	0.847	.041	6	view →
LAML	DFS	Median	All	0.441	0.310	.041	4	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MIR4650-2–KICH (DFS)

Open the KICH breakdown →