MIR4648

Across TCGA pan-cancer cohorts, MIR4648 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR4648’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where MIR4648 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4648 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

STAD, COAD, and KICH are the cancer types where MIR4648 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4648 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.664	<.001	8	view →
COAD	Female	All	+1.014	<.001	7	view →
KICH	All	All	−0.274	.004	3	view →
LUAD	All	All	+0.341	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR4648–STAD

Open the STAD breakdown →