MIR4635

Across TCGA pan-cancer cohorts, MIR4635 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated MIR4635 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR4635 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR4635 expression acts as an unfavorable survival marker, although some lineages such as HNSC and STAD show a favorable association.

HNSC, THCA, and STAD are the cancer types where MIR4635 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.701	0.545	<.001	141	view →
THCA	OS	Median	II,III,IV	0.897	0.992	<.001	62	view →
STAD	OS	Median	All	0.456	0.295	.003	59	view →
UCS	DFS	Tertile	III,IV	0.631	0.268	.002	56	view →
OV	OS	Quartile	IV	0.241	0.551	.002	50	view →
COAD	DFS	Quartile	II,III,IV	0.313	0.744	.001	46	view →
MESO	OS	Median	II,III,IV	0.193	0.391	.003	46	view →
LUAD	DFS	Median	IV	0.456	0.903	<.001	45	view →
READ	DFS	Quartile	III,IV	0.546	0.864	.002	43	view →
UCEC	OS	Median	All	0.520	0.799	<.001	42	view →
UVM	OS	Quartile	III,IV	0.347	0.876	.021	32	view →
PRAD	OS	Quartile	All	0.891	1.000	.007	24	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

MIR4635–HNSC (DFS)

Open the HNSC breakdown →