MIR4540

Across TCGA patient cohorts, MIR4540 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,866 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4540-associated GO terms across cancer lineages are Regulation of B cell activation, Maintenance of location in cell, and B cell activation. Each is linked with MIR4540 in more than 5 cancer types. Because this analysis shows association rather than direction, both MIR4540-to-partner and partner-to-MIR4540 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of B cell activation grouped by MIR4540-low versus MIR4540-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4540→partner) and Y-score (partner→MIR4540) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Regulation of B cell activation →	+0.106	+0.073	<.001	<.001	3	6
LUSC	Maintenance of location in cell →	+0.065	+0.083	<.001	<.001	3	6
LUSC	B cell activation →	+0.106	+0.078	<.001	<.001	3	6
STAD	Regulation of membrane lipid distribution →	+0.046	+0.177	<.001	<.001	3	5
LAML	Regulation of glutamate receptor signaling pathway →	+0.111	+1.079	.001	.004	3	5
LUSC	Antigen receptor-mediated signaling pathway →	+0.120	+0.103	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,866 associations by consensus.

Regulation of B cell activation by MIR4540 expression — LUSC

Explore this box plot interactively →