MIR4536-2

Across TCGA pan-cancer cohorts, MIR4536-2 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR4536-2 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MIR4536-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4536-2 expression acts as an unfavorable survival marker.

THCA, KIRC, and DLBC are the cancer types where MIR4536-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.240	0.931	<.001	51	view →
KIRC	DFS	Tertile	II,III,IV	0.180	0.656	.026	36	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	36	view →
LAML	DFS	Tertile	All	0.166	0.575	.014	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	27	view →
SKCM	OS	Tertile	III,IV	0.250	0.801	<.001	27	view →
UCEC	DFS	Tertile	All	0.711	0.841	.024	12	view →
ACC	DFS	Tertile	All	0.140	0.666	.049	9	view →
THYM	OS	Tertile	All	0.544	0.945	.018	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR4536-2–THCA (OS)

Open the THCA breakdown →