MIR4520-1

Across TCGA pan-cancer cohorts, MIR4520-1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MIR4520-1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MIR4520-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4520-1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

COAD, HNSC, and KICH are the cancer types where MIR4520-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.804	0.899	<.001	67	view →
HNSC	DFS	Median	II,III,IV	0.381	0.263	.002	47	view →
KICH	OS	Quartile	All	0.875	0.994	.005	38	view →
UCS	DFS	Tertile	II,III,IV	0.557	0.089	.003	36	view →
TGCT	DFS	Quartile	II,III,IV	0.586	0.996	.005	24	view →
LUAD	OS	Quartile	All	0.861	0.610	<.001	23	view →
ESCA	OS	Quartile	III,IV	0.686	0.441	.021	15	view →
STAD	DFS	Tertile	II,III,IV	0.541	0.690	.025	14	view →
BRCA	DFS	Median	III,IV	0.861	0.725	.006	12	view →
UCEC	OS	Quartile	All	0.815	0.888	.017	12	view →
CESC	OS	Quartile	IV	0.644	0.166	.006	12	view →
ACC	DFS	Median	II,III,IV	0.225	0.574	.034	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MIR4520-1–COAD (OS)

Open the COAD breakdown →