MIR4518

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR4518 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,497 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4518-associated GO terms across cancer lineages are Lymphocyte activation involved in immune response, B cell activation, and Regulation of adaptive immune response. Each is linked with MIR4518 in more than 17 cancer types. Because this analysis shows association rather than direction, both MIR4518-to-partner and partner-to-MIR4518 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lymphocyte activation involved in immune response grouped by MIR4518-low versus MIR4518-high in COAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4518→partner) and Y-score (partner→MIR4518) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADLymphocyte activation involved in immune response →+0.080+0.050<.001.005318
COADB cell activation →+0.102+0.101<.001.003317
STADRegulation of adaptive immune response →+0.049+0.610<.001<.001317
SKCMNegative regulation of cell activation →+0.053+0.099<.001<.001317
COADNegative regulation of leukocyte apoptotic process →+0.081+0.081<.001.002317
COADAntigen receptor-mediated signaling pathway →+0.097+0.109<.001.002317
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,497 associations by consensus.

Lymphocyte activation involved in immune response by MIR4518 expression — COAD

Box plot of Lymphocyte activation involved in immune response in MIR4518-low vs MIR4518-high samples in COAD.

Explore this box plot interactively →

Exploration