MIR4514

Across TCGA pan-cancer cohorts, MIR4514 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of MIR4514’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR4514 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR4514 is over-expressed in tumor, although a few such as LUSC and KIRP show the opposite, repressed pattern.

LUSC, KIRP, and LUAD are the cancer types where MIR4514 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4514 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.425	<.001	5	view →
KIRP	Male	All	−0.528	<.001	4	view →
LUAD	Female	II,III,IV	−0.636	.022	2	view →
HNSC	Male	II,III,IV	−0.214	.030	2	view →
THCA	Male	II,III,IV	−0.558	.044	1	view →
KICH	Male	II,III,IV	−0.420	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

MIR4514–LUSC

Open the LUSC breakdown →