Across TCGA pan-cancer cohorts, MIR450B RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR450B’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where MIR450B RNA is repressed in tumor relative to normal tissue. In most cancer types MIR450B is over-expressed in tumor, although a few such as UCEC and KICH show the opposite, repressed pattern.

UCEC, KICH, and BRCA are the cancer types where MIR450B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR450B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.339	.010	2	view →
KICH	All	All	−0.184	.028	2	view →
BRCA	All	III,IV	−0.121	.037	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MIR450B RNA expression & survival · all MIR450B data types