MIR450A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR450A2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR450A2-associated genes across cancer lineages are RNU6-1082P, PDCL2P1, and RN7SL554P. Each is linked with MIR450A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR450A2-to-partner and partner-to-MIR450A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR450A2→partner) and Y-score (partner→MIR450A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-1082P →+0.689+5.551<.001.00431
UCECPDCL2P1 →+0.284+5.484.003.00531
UCECRN7SL554P →+0.341+5.771<.001.00331
UCECHMGB3P15 →+0.159+5.186.004.00731
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

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