MIR450A1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR450A1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR450A1-associated genes across cancer lineages are RN7SL627P, NAPGP2, and MIR5696. Each is linked with MIR450A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR450A1-to-partner and partner-to-MIR450A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR450A1→partner) and Y-score (partner→MIR450A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL627P →+0.163+5.027<.001.00431
UCECNAPGP2 →+0.166+4.852<.001.00631
UCECMIR5696 →+0.767+5.123<.001.00431
UCECSNORD116-8 →+1.254+4.499<.001.00531
UCECRNA5SP222 →+0.485+5.877<.001.00131
UCECLINC02590 →+0.257+4.936<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration