Q-omics provides the consensus-scored MIR4506 profile across patient tissues and cancer cell-line models. MIR4506 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, MIR4506 is differentially expressed in 10, with the highest sampling consensus in BLCA. Additionally, MIR4506 RNA expression shows 10,931 significant gene co-expression associations, with the highest sampling consensus in SARC. Together, these results highlight UCS, BLCA, and SARC as cancer lineages where MIR4506 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4506 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4506 survival associations across molecular data types. MIR4506 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4506 RNA expression–survival associations across cancer types. High MIR4506 expression shows unfavorable associations in UVM, LIHC and KIRC, but favorable associations in UCS, ESCA and DLBC. The UCS Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .005). Together, the overview and detailed table identify UCS as the clearest survival context for MIR4506 RNA expression.
This table summarizes MIR4506 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4506. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4506 shows lower tumor expression in BLCA, UCEC, READ, PAAD, COAD and PRAD. The BLCA box plot shows higher MIR4506 RNA expression in normal versus tumor tissue (log2 FC = −0.943, t-test p = .001).
This table shows molecular features associated with MIR4506 in patient tissues and cancer cell lines. In patient samples, MIR4506 shows the broadest associations at the RNA and protein expression levels, with SARC recurring as the lineage with the largest associated feature set.
