MIR4497

Across TCGA pan-cancer cohorts, MIR4497 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR4497’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR4497 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4497 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

LUSC, KICH, and LIHC are the cancer types where MIR4497 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4497 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.327	<.001	5	view →
KICH	All	All	−0.240	.019	3	view →
LIHC	Female	II,III,IV	+0.203	.031	1	view →
LUAD	All	II,III,IV	+0.127	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR4497–LUSC

Open the LUSC breakdown →