MIR4495

Across TCGA patient cohorts, MIR4495 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,227 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4495-associated GO terms across cancer lineages are Negative regulation of release of cytochrome c from mitochondria, Regulation of proteolysis involved in protein catabolic process, and mRNA transport. Each is linked with MIR4495 in more than 4 cancer types. Because this analysis shows association rather than direction, both MIR4495-to-partner and partner-to-MIR4495 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of release of cytochrome c from mitochondria grouped by MIR4495-low versus MIR4495-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4495→partner) and Y-score (partner→MIR4495) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of release of cytochrome c from mitochondria →	+0.123	+0.182	<.001	.001	3	4
ESCA	Regulation of proteolysis involved in protein catabolic process →	+0.134	+0.158	<.001	.005	3	4
ESCA	mRNA transport →	+0.168	+0.277	<.001	.003	3	4
STAD	Regulation of carbohydrate metabolic process →	+0.088	+0.189	<.001	<.001	3	4
ESCA	Golgi lumen acidification →	+0.104	+0.170	<.001	.003	3	4
STAD	Response to carbohydrate →	+0.074	+0.172	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,227 associations by consensus.

Negative regulation of release of cytochrome c from mitochondria by MIR4495 expression — ESCA

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