MIR4489

Across TCGA pan-cancer cohorts, MIR4489 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MIR4489 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR4489 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4489 expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

KIRC, SKCM, and HNSC are the cancer types where MIR4489 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.535	0.714	<.001	134	view →
SKCM	OS	Median	All	0.412	0.273	<.001	114	view →
HNSC	OS	Median	III,IV	0.791	0.547	.001	82	view →
BLCA	DFS	Tertile	All	0.483	0.248	<.001	69	view →
ACC	OS	Quartile	All	0.530	0.830	.001	61	view →
MESO	DFS	Tertile	IV	0.320	0.815	.006	21	view →
PRAD	DFS	Median	All	0.678	0.875	.001	16	view →
CESC	DFS	Tertile	IV	0.784	0.311	.005	12	view →
READ	OS	Tertile	II,III,IV	0.863	0.335	.003	12	view →
SARC	DFS	Median	All	0.535	0.718	.002	12	view →
PAAD	OS	Tertile	All	0.478	0.270	.023	10	view →
LUSC	OS	Median	II,III,IV	0.536	0.778	.023	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

MIR4489–KIRC (OS)

Open the KIRC breakdown →