MIR4488

Across TCGA pan-cancer cohorts, MIR4488 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MIR4488 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MIR4488 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4488 expression acts as an unfavorable survival marker, although some lineages such as MESO and LIHC show a favorable association.

UCS, TGCT, and SKCM are the cancer types where MIR4488 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.103	0.699	<.001	108	view →
TGCT	OS	Tertile	II,III,IV	0.501	0.996	<.001	72	view →
SKCM	DFS	Tertile	All	0.286	0.618	.004	51	view →
UCEC	OS	Tertile	All	0.281	0.700	.003	48	view →
ACC	DFS	Tertile	All	0.160	0.679	.001	36	view →
HNSC	OS	Tertile	II,III,IV	0.132	0.756	<.001	36	view →
BRCA	OS	Tertile	IV	0.106	0.791	<.001	36	view →
LUSC	OS	Tertile	All	0.544	0.770	.007	36	view →
READ	DFS	Tertile	III,IV	0.254	0.635	.017	15	view →
THCA	OS	Tertile	III,IV	0.871	0.981	.014	12	view →
THYM	DFS	Tertile	All	0.700	0.924	.017	9	view →
MESO	DFS	Tertile	All	1.000	0.179	.041	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MIR4488–UCS (OS)

Open the UCS breakdown →