MIR4480

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR4480 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR4480 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR4480 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR4480 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, ACC, and KIRP are the cancer types where MIR4480 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSTertileIV1.0000.643.002144view →
ACCDFSTertileAll0.0500.636<.00157view →
KIRPDFSTertileIV0.0880.502<.00136view →
KIRCDFSTertileIV0.4670.671.01330view →
LUADOSTertileIII,IV0.8690.621.01330view →
READOSTertileAll0.2810.823<.00127view →
THCAOSTertileAll0.9410.987.03218view →
KICHDFSTertileAll0.1210.867.02315view →
SKCMDFSTertileIII,IV0.0980.655.0019view →
LIHCOSTertileAll0.2340.563.0256view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR4480–HNSC (DFS)

Kaplan–Meier survival curve for MIR4480 RNA-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration