Across TCGA pan-cancer cohorts, MIR448 RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated MIR448 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR448 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR448 expression acts as an unfavorable survival marker.

HNSC and STAD are the cancer types where MIR448 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	III,IV	0.118	0.665	<.001	153	view →
STAD	OS	Tertile	IV	0.111	0.433	.002	45	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MIR448 tumor-vs-normal RNA expression · all MIR448 data types