MIR4478

Across TCGA pan-cancer cohorts, MIR4478 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated MIR4478 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher MIR4478 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4478 expression acts as an unfavorable survival marker, although some lineages such as UCS show a favorable association.

BRCA, ESCA, and LUSC are the cancer types where MIR4478 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	IV	0.175	0.730	.005	36	view →
ESCA	OS	Tertile	All	0.195	0.872	<.001	36	view →
LUSC	OS	Tertile	III,IV	0.260	0.670	.026	27	view →
KIRP	OS	Tertile	All	0.693	0.889	.003	24	view →
UCS	DFS	Tertile	IV	0.981	0.514	.013	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
PCPG	DFS	Tertile	All	0.544	0.838	.046	6	view →
UCEC	DFS	Median	All	0.868	0.923	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

MIR4478–BRCA (DFS)

Open the BRCA breakdown →