MIR4462

Across TCGA pan-cancer cohorts, MIR4462 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated MIR4462 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher MIR4462 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4462 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LGG show a favorable association.

OV, LUSC, and BLCA are the cancer types where MIR4462 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	All	0.317	0.549	<.001	144	view →
LUSC	OS	Tertile	II,III,IV	0.276	0.703	.003	96	view →
BLCA	OS	Tertile	IV	0.094	0.594	<.001	63	view →
HNSC	OS	Tertile	All	0.870	0.365	.012	54	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	45	view →
LGG	DFS	Median	All	0.905	0.792	<.001	37	view →
DLBC	DFS	Tertile	All	0.458	0.872	.003	36	view →
PCPG	OS	Tertile	All	0.714	0.963	<.001	27	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
SARC	DFS	Tertile	All	0.118	0.591	.034	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
PRAD	OS	Tertile	All	0.964	0.995	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

MIR4462–OV (DFS)

Open the OV breakdown →