MIR4457

Across TCGA patient cohorts, MIR4457 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,427 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4457-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Mitotic cytokinesis, and Positive regulation of DNA repair. Each is linked with MIR4457 in more than 5 cancer types. Because this analysis shows association rather than direction, both MIR4457-to-partner and partner-to-MIR4457 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by MIR4457-low versus MIR4457-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4457→partner) and Y-score (partner→MIR4457) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of double-strand break repair via homologous recombination →	+0.096	+0.182	<.001	<.001	3	6
ESCA	Mitotic cytokinesis →	+0.117	+0.195	<.001	<.001	3	6
ESCA	Positive regulation of DNA repair →	+0.100	+0.177	<.001	<.001	3	6
STAD	Positive regulation of DNA metabolic process →	+0.102	+0.168	<.001	<.001	3	6
ESCA	Tubulin deacetylation →	+0.096	+0.201	<.001	.002	3	6
ESCA	Regulation of telomere capping →	+0.103	+0.182	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,427 associations by consensus.

Regulation of double-strand break repair via homologous recombination by MIR4457 expression — STAD

Explore this box plot interactively →