MIR4456

Across TCGA patient cohorts, MIR4456 RNA expression is significantly associated with the go_rna of many other GO terms, with 952 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4456-associated GO terms across cancer lineages are Tricuspid valve morphogenesis, Notch signaling pathway, and Fibroblast growth factor receptor signaling pathway. Each is linked with MIR4456 in more than 2 cancer types. Because this analysis shows association rather than direction, both MIR4456-to-partner and partner-to-MIR4456 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tricuspid valve morphogenesis grouped by MIR4456-low versus MIR4456-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4456→partner) and Y-score (partner→MIR4456) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Tricuspid valve morphogenesis →	+0.059	+0.530	.001	.006	3	2
LIHC	Notch signaling pathway →	+0.034	+0.052	.001	.003	3	1
LIHC	Fibroblast growth factor receptor signaling pathway →	+0.035	+0.073	.002	.008	2	2
STAD	Positive regulation of cell morphogenesis →	+0.058	+0.388	<.001	<.001	3	1
STAD	Negative regulation of peptidyl-threonine phosphorylation →	+0.051	+0.330	<.001	<.001	3	1
STAD	Regulation of synaptic vesicle priming →	+0.061	+0.186	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 952 associations by consensus.

Tricuspid valve morphogenesis by MIR4456 expression — ESCA

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