MIR4444-2

Across TCGA patient cohorts, MIR4444-2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,504 significant associations in total. OV shows the largest number of these associations.

The most reproducible MIR4444-2-associated GO terms across cancer lineages are Protein insertion into ER membrane by stop-transfer membrane-anchor sequence, Regulation of cell division, and Peptidyl-lysine modification. Each is linked with MIR4444-2 in more than 9 cancer types. Because this analysis shows association rather than direction, both MIR4444-2-to-partner and partner-to-MIR4444-2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into ER membrane by stop-transfer membrane-anchor sequence grouped by MIR4444-2-low versus MIR4444-2-high in LGG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4444-2→partner) and Y-score (partner→MIR4444-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.044	+0.107	<.001	<.001	3	10
ESCA	Regulation of cell division →	+0.030	+0.261	.003	.001	3	9
ESCA	Peptidyl-lysine modification →	+0.046	+0.395	.004	<.001	3	9
ESCA	Positive regulation of isotype switching →	+0.038	+0.314	.005	.002	3	8
OV	Positive regulation of DNA recombination →	+0.020	+0.185	<.001	<.001	3	8
ESCA	Positive regulation of mitotic cell cycle →	+0.035	+0.251	.004	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,504 associations by consensus.

Protein insertion into ER membrane by stop-transfer membrane-anchor sequence by MIR4444-2 expression — LGG

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