Across TCGA pan-cancer cohorts, MIR4432HG RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of MIR4432HG’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR4432HG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4432HG is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.
BRCA, COAD, and THCA are the cancer types where MIR4432HG tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4432HG RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.