MIR4422

Across TCGA pan-cancer cohorts, MIR4422 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MIR4422 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher MIR4422 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR4422 expression acts as an unfavorable survival marker, although some lineages such as OV and ESCA show a favorable association.

OV, READ, and LGG are the cancer types where MIR4422 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	III,IV	0.857	0.521	.002	90	view →
READ	DFS	Tertile	All	0.269	0.819	.009	45	view →
LGG	DFS	Tertile	All	0.482	0.748	<.001	30	view →
LAML	DFS	Tertile	All	0.144	0.431	.041	18	view →
LIHC	DFS	Tertile	All	0.043	0.543	<.001	18	view →
SKCM	OS	Tertile	III,IV	0.193	0.729	<.001	12	view →
ESCA	OS	Tertile	III,IV	0.814	0.368	.042	12	view →
THYM	DFS	Tertile	II,III,IV	0.083	0.881	<.001	9	view →
KIRP	OS	Tertile	All	0.795	0.950	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MIR4422–OV (DFS)

Open the OV breakdown →