MIR4330

Across TCGA patient cohorts, MIR4330 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,557 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MIR4330-associated GO terms across cancer lineages are Chromatin looping, Positive regulation of non-canonical NF-kappaB signal transduction, and Regulation of oxidative stress-induced intrinsic apoptotic signaling pathway. Each is linked with MIR4330 in more than 2 cancer types. Because this analysis shows association rather than direction, both MIR4330-to-partner and partner-to-MIR4330 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromatin looping grouped by MIR4330-low versus MIR4330-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4330→partner) and Y-score (partner→MIR4330) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Chromatin looping →	+0.073	+0.046	.007	.004	3	2
KIRC	Positive regulation of non-canonical NF-kappaB signal transduction →	+0.094	+0.033	<.001	.007	3	2
KIRC	Regulation of oxidative stress-induced intrinsic apoptotic signaling pathway →	+0.120	+0.032	<.001	.006	3	2
KIRC	Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway →	+0.120	+0.030	<.001	.005	3	2
KIRC	Negative regulation of response to wounding →	+0.083	+0.017	<.001	.005	3	2
KIRC	Regulation of Golgi organization →	+0.108	+0.018	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,557 associations by consensus.

Chromatin looping by MIR4330 expression — ESCA

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